3,3'-Diindolylmethane
3, 3-Diindolylmethane (DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables. At the present time, DIM is used to treat Recurring Respiratory Papillomatosis, a rare respiratory disease with tumors in the upper respiratory tracts caused by the Human Papilloma Virus.
Features
English Name: 3,3'-Diindolylmethane
Specs: 99% HPLC
Appearance: White or almost white powder
Basic Information
English Name: 3,3'-Diindolylmethane
Sepcs: 99%HPLC
Other Name: 3-(1H-Indol-3-ylmethyl)-1H-indole; 3,3'-Methylenebis-1H-indole; DIM
Appearance: White or almost white powder
CAS No.: 1968-05-4
Molecular formula: C17H14N2
Function
Cervical Dysplasia Research:
Preliminary studies indicate that administering a specific diindolylmethane product, BioResponse-DIM, for 12 weeks does not significantly improve disease markers in women with cervical dysplasia, an abnormal growth of cells in the cervix.
Prostate Cancer Studies:
Early research shows promising results for men with prostate cancer. Taking BioResponse-DIM for 28 days has been found to lower prostate-specific antigen (PSA) levels, which are used to gauge the progress of prostate cancer.
Prostate Health:
DIM may also help in preventing benign prostatic hypertrophy (BPH), a non-cancerous enlargement of the prostate gland.
Premenstrual Syndrome (PMS):
Diindolylmethane can potentially be used to alleviate the symptoms of premenstrual syndrome.
Broader Applications:
There is ongoing research into other conditions where DIM might prove beneficial.
Application
Reduces Inflammation:
DIM exhibits strong anti-inflammatory effects. As a partial CB2 receptor agonist, it helps mitigate neuroinflammation by interacting with the endocannabinoid system. Additionally, DIM acts on GPR84 and shows potent inhibition of COX-2, further protecting against inflammation.
Promotes Detoxification and Antioxidant Production:
DIM enhances the body's detoxification processes and boosts antioxidant production through the activation of AhR and Nrf2 signaling pathways. It modulates AhR to promote the transcription of genes that increase detoxification enzymes, including phase I cytochrome P450 (CYP) enzymes. Furthermore, it induces the expression of the transcription factor Nrf2, which has robust antioxidant and detoxifying effects.
Diindolylmethane (DIM) stands out for its multifaceted health benefits. It plays a crucial role in fighting cancer, reducing inflammation, and enhancing the body's detoxification and antioxidant mechanisms through its interaction with various biological pathways and receptors.
Specifications Sheet
| Content | Specification |
| Appearance | Off-white to light yellow Powder |
| Assay(HPLC) | ≥99% |
| Melting Point | 96 -100°C |
| Loss on drying | ≤5.0% |
| Residual on Ignition | ≤0.5% |
| Bulk density (loose) | 0.15-0.45g/ml |
| Arsenic | ≤1ppm |
| Pb | ≤5ppm |
| Microbiological Control | |
| Total Plate Count | <500CFU/G |
| Mould &Yeast | <100CFU/G |
| E.Coli | Absent |
| Salmonella | Absent |
| Stahylococcus aureus | Absent |
| Pseudomona aeruginosa | Absent |
Shipping & Storage
Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Quality&Certifications
