N-acetylneuraminic acid
N-Acetylneuraminic acid refer to a family of neuraminic acids which contain nine-carbon acidic amino monosaccharides. The most important member of the sialic acid is N-Acetylneuraminic acid (NeuAc or NANA), occurring most abundantly in glycoproteins and glycolipids.
Features
Product Name:N-Acetylneuraminic acid
Sialic acid; NANA
Standard Assay: 99%
CAS NO.:131-48-6
Basic Information
| Product name: | N-acetylneuraminic acid/NANA |
| Other name: | Sialic acid |
| Specification: | 98% |
| CAS No.: | 131-48-6 |
| Molecular Weight: | 309.2699 |
| Appearance: | White crystalline powder |
| Molecular Formula: | C11H19NO9 |
Function
Key Role in Drug Development:
N-Acetylneuraminic acid is critical in the R&D of carbohydrate-based drugs. It is a focal point in research due to its role in synthesizing and screening bioactive substances. Notably, it has shown promise in combating metastasis, Alzheimer’s disease, viral infections, and inflammation. A new generation of anti-influenza drugs derived from sialic acid is already available, and an anti-Alzheimer’s medication is on the horizon. Research indicates that sialic acid is vital for brain and peripheral nerve nutrition.
Functional Food Ingredient:
N-Acetylneuraminic acid is now widely used in functional foods, providing various health benefits.
Enhancing Infant Nutrition:
When added to infant milk powder, N-Acetylneuraminic acid can enhance a baby’s cognitive development and memory, potentially boosting intelligence.
Anti-Inflammatory and Immunity Booster:
This compound exhibits strong anti-inflammatory properties and enhances the body’s immune response.
"Brain Gold" for Mental Development:
Revered as "brain gold," N-Acetylneuraminic acid is crucial for mental development, supporting cognitive functions and growth.
Cosmetics, Food, and Health Supplements:
N-Acetylneuraminic acid is also utilized in cosmetics, food p
Application
Foundation for Neuraminidase Inhibitors and Bioactive Compounds:
N-Acetylneuraminic acid serves as a critical component in the production of neuraminidase inhibitors, glycolipids, and various synthetically derived bioactive products. Its role is essential in developing drugs targeting viral infections and other medical conditions.
Key Ingredient in Glyconutrient Supplements:
As a beneficial glyconutrient, N-Acetylneuraminic acid could play a valuable role in dietary supplements, promoting overall health and well-being.
Versatile Biological Roles:
Commonly known as sialic acid or Neu5Ac, N-Acetylneuraminic acid is a naturally occurring carbohydrate involved in numerous biological functions. These include:
-
- Regulation of Blood Protein Half-Life: Helps maintain the stability and longevity of blood proteins.
- Toxin Neutralization: Assists in neutralizing various toxins, protecting the body from harmful substances.
- Cellular Adhesion: Facilitates cell-to-cell adhesion, playing a crucial role in cellular communication.
- Glycoprotein Protection: Protects glycoproteins from degradation, ensuring their functional integrity.
Biochemical Synthesis:
N-Acetylneuraminic acid is a starting reagent for biochemical derivatives used in synthesizing various pharmaceuticals, highlighting its importance in medical research and drug development.
Specifications Sheet
| ITEM | STANDARD | TEST RESULT |
| Assay | ||
| Sialic Acid | ≥98% | 98.40% by HPLC |
| Physical &Chemical Control | ||
| Appearance | White or off-white powder | Complies |
| Odor | No off-smell | Complies |
| Taste | Characteristic | Characteristic |
| Particle Size | 98% pass 80 mesh | Complies |
| Loss on Drying | ≤0.5% | 0.33% |
| Residue on lgnition | ≤1.0% | 0.28% |
| Acetic acid | ≤0.05% | Complies |
| Sulfates | ≤0.005% | Complies |
| Chloride | ≤0.0005% | Complies |
| Melting point | 184-186℃ | 185℃ |
| Optical rotation[α]D20℃(H2O) | -30.0 ~ -34.0 | -31.6 |
| Heavy Metals | ||
| Total Heavy Metals | ≤10ppm | <10popm |
| As | ≤0.4ppm | <0.4popm |
| Pb | ≤0.4ppm | <0.4ppm |
| Cd | ≤0.2ppm | <0.2ppm |
| Hg | ≤0.1ppm | <0.1ppm |
| Solvent Residual | ≤5000ppm | Complies |
| Microbiological Control | ||
| Aerobic bacterial count | ≤500cfu/g | 67cfu/g |
| Conclusion | Conform with specification, Non-GMO, Allergen Free | |
| Storage | Store in cool and dry places. Keep away from strong light and heat. | |
| Packing | By 25kgs/Drum,inner by plastic bag | |
Shipping & Storage
Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Quality&Certifications
